In 1998, Laboratoires EXPANSCIENCE, eager to achieve strong ties with the French Rheumatology community and participate in the development of clinical and basic research in the field of osteoarthritis, decided to create, with the participation of the French Society of Rheumatology, the EXPANSCIENCE OSTEOARTHRITIS AWARD FOR CLINICAL RESEARCH and the EXPANSCIENCE OSTEOARTHRITIS AWARD FOR BASIC RESEARCH.
These awards honour two French-speaking researchers for the scientific value and innovation of their work. This work must be under publication or have been published during the course of the year. Each winner receives a prize of 3,820 Euros. The awards are announced during the plenary session of the Osteoarthritis Congress of the French Society of Rheumatology which provides the opportunity for a friendly get-together between jury members and candidates on the EXPANSCIENCE stand. The awards are given based on the dossiers by two separate and independent juries:
The clinical research Jury is made up of: Bernard BANNWARTH (CHU Pellegrin, Bordeaux), Pierre BOURGEOIS (CHU Pitié-Salpêtrière, Paris), Xavier CHEVALIER (CHU Henri-Mondor, Créteil) and Damien LOEUILLE (Hôpital Brabois – Vandoeuvre-les-Nancy).
And that of basic research: Francis BERENBAUM (CHU St Antoine, Paris),Yves HENROTIN (CHU Sart-Tilma, Liège), François RANNOU (Hôpital Cochin – Paris), Pascal RICHETTE (CHU Lariboisière, Paris).
The ARTHROSIS AWARDS of the Laboratoires EXPANSCIENCE are open to all hospital doctors of a French-speaking service (heads of services, hospital practitioners, heads of clinics, interns, ...) the applications are to be withdrawn from the agency NUKLEUS - nukleus@nukleus.fr - and are to be submitted in September.
| HISTORY OF THE ARTHROSIS AWARD 1998-2019 | ||
| Prize for Clinical Research | Prize for Basic Research | |
| 2019 | Dr Augustin Latourte | Pr Cécile Lambert |
| Article | "Chondrocalcinocis of the knee and the risk for osteoarthritis progression : data from the KHOALA cohort" | "Type II collagen peptide Coll2-1 is an actor of synovitis" |
| 2018 | Thomas Funck Brentano | Yves Henrotin |
| Article | "Independent risk markers and their causality for knee, hip and hand osteoarthritis : a Mendelian randomization study in the UK Biobank" | "Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilague in vivo" |
| 2017 | Christelle Nguyen | Eymard Florent |
| Article | "Intradiscal Glucocorticoid Injection for patients with Chronic Low Back Pain associated with active discopathy" | "Knee and hip intra-articular adipose tissues (IAAATs) compared with autologous subcutaneous adipose tissue: a specific phenotype for a central player in osteoarthritis" |
| 2015 | Paul Ornetti | Wafa Bouaziz |
| Article | "Test-retest reliability and responsiveness of centre of pressure measurements in patients with hip osteoarthritis" | "Rôle de HIF1 au cours de l'arthrose" |
| 2014 | Charline Estublier | Florent Eymard |
| Article | "Severe spine osteoarthritis is associated with all cause mortality and abdominal aortic calcification in a cohort of older men - the prospective MINOS study" | "Induction of an inflammatory and prodegradative phenotype in autologous fibroblast-like synoviocytes by the infrapatellar fat pad from patients with knee osteoarthritis" |
| 2013 | Vincent Burki | Hang Korng EA |
| Article | "Rapidly destructive tibiofemoral knee osteoarthritis : Clinicoradiological presentation and outcome after global medical treatment including non-arthroscopic joint lavage plus corticosteroid injection. A single center retrolective study" | "Pathogenic role of basic calcium phosphate crystals in destructive arthropathies" |
| 2012 | Florence Tubach | Elise Duval |
| Article | "Minimal Clinically Important Improvement and Patient Acceptable Symptomatic State in pain and function in rheumatoid arthritis, ankylosing spondylitis, chronic back pain, hand osteoarthritis, and hip and knee osteoarthritis : the REFLECT multinational study" | "Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering" |
| 2011 | Thierry Conrozier | Catherine Baugé |
| Article | "Early effect of hyaluronic acid intra-articular injections on serum and urine biomarkers in patients with knee osteoarthritis : An open-label observational prospective study" | "Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta" |
| 2010 | Pascal Richette | Natacha Thelier |
| Article | "Benefits of massive weight loss on symptoms,systemic inflammation and cartilague turnover in obese patients with knee osteoarthritis" | "Design of group IIA secreted/sinovial Phospholipase A2 inhibitors:An oxadiazolone derivative suppresses chondrocyte prostaglandin E2 secretion" |
| 2009 | Pas de prix | Christelle Sanchez |
| Article | "Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts" | |
| 2008 | Philippe Ravaud | Ea Hang-Korn |
| Article | "External validity is neglected in reports of randomized trials – the example of hip and knee osteoarthritis" | "Annexin V Overexpression Increased Joint Chondrocyte Apoptosis Induced by Basic Calcium Phosphate Crystals" |
| 2007 | Raphaële Seror | Pascal Richette |
| Article | "Individualizing the WOMAC function subscale : Incorporating patient’s priorities for improvement to measure functional impairment in knee or hip osteoarthritis" | "Oestrogens inhibit interleukin 1 beta-mediated nitric oxyde synthase expression in articular chondrocytes through nuclear factor-kappaB impairment" |
| 2006 | Florence Tubach | Christine Chappard |
| Article | "Feeling good rather than feeling better matters more patients" | "Subchondral bone micro-architectural alterations in osteoarthritis : a sunchrotron micro-computed tomography study" |
| 2005 | Damien Loeuille | Florence Legendre |
| Article | "Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee" | "Implication des voies de signalisation de l’IL-6 dans la régulation des molécules matricielles et de leurs enzymes de dégradation chez les chondrocytes articulaires" |
| 2004 | Florence Tubach | Pascal Richette |
| Article | "Using patients’ and rheumatologists’ opinions to specify a short form of the WOMAC function subscale" | "A peroxisome proliferator-activated receptor-a-dependent pathway increases interleukine-1 receptor antagonist production in chondrocytes" |
| 2003 | Philippe Goupille | Pierre Gillet |
| Article | "Safety and efficacy study of intra-articular injection of IL-1ra in patients with painful osteoarthritis of the knee : a double blind multicentric study" | "Thérapie génique et cartilage articulaire : intérêt de l’électroporation" |
| 2002 | Serge Poiraudeau | Christos Chadjichristos |
| Article | "Algo-functional assessment of knee osteoarthritis : comparison of the test-retest reliability and construct validity of the Womac and Lequesne indexes" | "Effets du TGF-ß1 sur l’expression du collagène de type II dans des cultures de chondrocytes différenciés : implication des facteurs de trascription Sp1 et Sp3" |
| 2001 | Xavier Chevalier | Damien Loeuille |
| Article | "Tissue inhibitor of metalloprotease-1 (TIMP-1) serum level may predict progression of hip osteoarthritis" | "Magnetic resonance imaging of normal and osteoarthritic cartilage" |
| 2000 | Thierry Conrozier | Chafik Ghayor |
| Article | "Serum levels of YKL-40 and C reactive protein in patients with hip osteoarthritis and healthy subjects : a cross sectional study" | "La régulation transcriptionnelle du gène de collagène de type II" |
| 1999 | Xavier AYRAL | Pas de prix |
| Article | "Validation de la quantification des lésions du cartilage du genou en IRM, en utilisant le score cartilagineux de la Société Française d’Arthroscopie" | |
| 1998 | Philippe Ravaud | Karim Boumediene |
| Article | ||
Osteoarthritis Awards Expanscience in 2019
The prize for Clinical Research was awarded to Dr Augustin Latourte ( Hôpital Lariboisière - Paris) : for his work : « Chondrocalcinocis of the knee and the risk for osteoarthritis progression : data from the KHOALA cohort ».
And the prize for Basic Research was awarded Pr Cécile Lambert (CHU Sart-Tilman -Liège) for : « Type II collagen peptide Coll2-1 is an actor of synovitis ».
